反应实例

黄鸣龙改进法，此反应会消除一分子乙烯。

黄鸣龙改进法。

A mixture of 18.2 g of benzophenone, 7 g of sodium hydroxide, 100 mL of triethylene glycol and 10 mL of 85% hydrazine hydrate was refluxed for 1 h. Then the condenser was removed until the temperature of the solution was had reached 195~200 oC, when refluxing was continued for about three hours. The mixture was cooled and extracted with ether. The ether residue on distillation over sodium gave 14.0 g (83.3%) of pure hydrocarbon, b. p. 149 oC at 29 mmg.

A reaction with 14.2 g (0.1 mol) of the ketone, 9 mL (0.18 mol) of hydrazine hydrate, 20 g of sodium and 400 mL of dithethlene glycol was carried out at 170-190 o for sixty-eight hours. After dilution with water, extraction with ether. The organic layer was washed in turn with water, dilute hydrochloric acid, and again with water. The extract was dried over anhydrous magnesium sulfate. Removal of solvent left the crude hydrocarbon, which was redistilled over sodium to give 8.95 g (70 %) of 2,6-dimethylheptane, bp 131-133 oC。

相关文献

1. (a) Kishner, N. J. Russ. Phys. Chem. Soc. 1911, 43, 582